I am not a 4 stroke expert, but I think I can help. For starters, the tuning philosophy is the same. The engine doesnt matter to the kart (necessarily). What matters is the kart, axle, tire compound, where/how hop condition exists, etc.
Now, those things are often very different for a 4 cycle guy vs a 2 cycle guy, but the strategy is the same. TJ is spot on. What is often different is what is causing the hop. Overloading the outside rear is not the only thing that can cause a hop. Setting the inside rear down too soon can cause it or even not lifting the inside rear enough.
In a 4 cycle, we rarely use enough lift to actually overload the outside rear. Mostly because we don’t have the power to overcome using that much energy. However, it does happen. All of this needs to be thought about when “fixing your hop issue”. Hence, why people may all fix “hop” differently. Because they are all actually fixing different things.
As the late Al Nunley would say. “This is called tuning and tuning is hard.”