I have experienced “four-stroking”. When I went to test the 100cc at DKC, it wasn’t hitting the top end properly. I brought it back to pits and Mike said it was “four stroking”. He hopped in the kart and proceeded to tear around in concentric circles while fiddling with the needles. Once he was done, it ran fine and hit top end and sounded normal.
Edit: TJ brings up Al and EGT, perhaps this thread: